Genetics (BIOL 2416) is a one-semester course at Tyler Junior College, designed to fit into the curriculum of biology majors, health science majors, pre-medicine, pre-dentistry, pre-pharmacy, pre-veterinary medicine, pre-physical therapy, and any other student interested in heredity.

One year of biology (8 semester hours) is required as a prerequisite. Concurrent enrollment in general chemistry or organic chemistry is recommended.

Classes meet 3 hours of lecture and 3 hours of lab each week. Off-campus trips to facilities that reinforce principles and application of genetic information is required.

Lab includes maintaining a fruit fly culture for various experiments, human karyotyping, probability and statistics, gel electrophoresis, and using the Internet to access up-to-date information.

Required course materials include a textbook, a lab guide, and a notebook.

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Course Outline 

	Introduction and Historical Perspectives   
	Mendelian Genetics
		Principles of Segregation
		Symbols and Terminology
		Monohybrid Crosses
		Principles of Independent Assortment   
	Probability in Mendelian Inheritance
		Hypotheses
		Chi-Square
		Independent Assortment & Probability
		Pedigree Analysis   
	Cell Mechanics
		Cell Cycle
		Gamete Formation
		Spore Formation
		Meiosis & Mendel's Principles   
	Sex Determination & Sex Linkage
		Balance Concept
		Y Chromosome
		X Chromosome
		Single Genes
		External Environment
		Sex Differentiation
		Sex-influenced Dominance
		Sex-limited gene expression
		Sex Linkage   
	Genetic Material
		DNA, The Genetic Material
		Replication of DNA
		Eukaryote Chromosome Structure
		Eukaryotic Chromosome Replication   
	Linkage, Crossing Over & Chromosome Mapping
		Linkage and Crossing Over; cytological basis
		Chromosome Mapping
		Two and Three Factor Crosses
		Interference
		Ordered and Unordered Tetrad Analysis
		Molecular Mechanisms of Crossing Over   
	Recombination in Bacteria
		Transformation
		Transduction
		Conjugation
		Breakage and Reunion
		Plasmids, Episomes   
	Gene Expression
		One Gene-One Polypeptide Concept
		Genetic Control of Metabolism
		Phenocopies
		Protein Synthesis
		Genetic Code
		Colinearity   
	Mutation
		Spontaneous  vs.  Induced
		Random  vs.  Environment Directed
		Phenotypic Effects
		Molecular Basis of Mutation
		Radiation-Induced Mutation
			Base Analogs
			Nitrous Acid
			Alkylating & Hydroxylating Agents
		Correlation Between Mutagenicity and Carcinogenicity
		Mutable Genes
		Viral Chromosomes as Mutators
		Practical Applications of Mutations
		Mutations and Humans   
	Genetic Fine Structure
		Concepts of the Gene
		Fine Structure of the Phage T4 R11 Locus
		Deletion Mapping
		Electron Microscope Mapping
		Complex Loci in Eukaryotes
		Multiple Alleles
		Salivary Gland Chromosomes
		Recombinant DNA and Gene Cloning
		Restriction Enzyme Cleavage Sites of Chromosomes
		Nucleotide Sequences   
	Regulation of Gene Expression and Development
		The Operon Model
		Feedback
		Transcription on Lampbrush Chromosomes
		Hormonal Control of Transcription
		Z-DNA	
		Oncogenes   
	Chromosome Aberrations
		Polytene Chromosomes
		Deficiencies/Duplications/Inversions/Translocations
		Position Effects
		Human Chromosome Techniques   
	Variation in Chromosome Number
	Extranuclear Inheritance Mechanisms
	Multiple Gene Inheritance
	Population Genetics
	Genetics of Behavior